Insights into Inflammation, Gut Microflora, Immunity,
and the Nervous System
Cordell E Logan, ND
Dr. Paul Yanick was concerned with the detrimental effects of synthetic vitamins and other food nutrients. This began his research into nutrition and what the body needs to remain healthy. From the website, aaqm.org, the following excerpt gives some background:
Nobel Prize Laureate, Dr. Szent Györgyi who discovered vitamin C, found that vitamin C in foods was far superior to synthetic ascorbic acid. Intrigued by this research, Dr. Yanick researched food-nutrient concentrates with a physician in New Jersey, finding that only food-based nourishment could improve nerve and hearing function (Journal of the American Audiology Society, 1975:2). He discovered that fermented protein formats of food were critical to restore cell function and could bypass weak digestion and this research confirmed by another Nobel Prize scientist (Journal of Cell Biology, 1975).
Observing other Nobel Laureate research, Dr. Yanick experimented with commensal microbiotica (Nature 1983:301; Cell 1985:42; Science 228:1985) discovering novel ways to re-colonize the gut after antibiotic or natural anti-infective agents destroyed the gut microbiotica. This discovery revealed how quorum-fermented™ nutrients could turn on or activate gut microbiotica and, years later, Dr. Breaker of Yale University reported that microbiotica had riboswitches functioning as “vital regulators of critical nutrient supplies” (Nature 2007:447; Science 2008:321; Future Microbiology 2009:4; Nature 2009:462).
In context with our body functions, “commensal” implies a symbiotic relationship in which one organism derives benefit and the other is unharmed. This is used mostly in context with gut microflora. The term “synbiotic” (n and not m) here means both prebiotic and probiotic beneficial bacterial relationships. The probiotic bacteria, such as found in yogurt, do better if they have proper prebiotic nutrients upon which to function. Some think as high as 90% of the cells in our body are commensal organisms.
The autonomic nervous system (ANS) with its two text divisions, the sympathetic nervous system, SNS, and the parasympathetic nervous system, PNS), and the peripheral nervous system, PNS, all function closely with the digestive and immune systems. We say “text” because some think we have a third division of the ANS. See article Autonomic Nervous System Update. The key player in switching on proper digestion is the parasympathetic nervous system, and more specifically, the vagus nerve.
The ANS directly innervates the liver cells and has powerful metabolic control over regeneration that exceeds that of stem cell activity.
The United States is one of the few countries that places so little importance on fermented foods, such as sauerkraut, yogurt, etc. This is a major reason for poor health in the U.S.
Nutrients created in natural fermentation open the lock and thereby take their role that is missing in USP vitamins (synthetic) and inorganic non-covalent minerals.
Infectious microbes form biofilms. Biofilms are stubborn infections found all over in the body. Biofilms often follow antibiotic and even some so-called natural anti-infective agents (silver included). These can impair detoxification of the body. Much of this research has been done at the Center for Biofilm Engineering at Montana State University in Bozeman. The innate immune system can only become fully operational when commensal cells are plentiful and able to attack overlooked, hidden, or treatment-resistant biofilms. The drugs that hit the COX-2 and LOX pathways only address about 15 to 20% of the problem, and ignore the rest, and that has heavy implications with the vagus nerve. Hypovagal issues include anxiety, nervousness, phobias, and insomnia. Yeast and fungal infections can ensue. Aging is related to decreased vagus nerve functioning.
A biofilm situation involves anaerobic tissue. In the gut this can induce IBS, leaky-gut, and related conditions. Antioxidants here? Better think oxygen instead.
Another missing link in correcting health problems is what the late Dr. Albert Krueger called “positive ion poisoning” (PIP). This is a toxic condition caused by toxicants with a positive ionic charge (in this context, positive does not mean good, and negative as bad; but atoms can carry a positive or a negative charge). Within the cell, mitochondrion electron transport can relate to free radical pathology that can cascade down into gut inflammation (T5-T8). When toxins carry a positive charge, they cannot be removed with most current methods of detoxification, including oral and IV chelation, ionic foot baths, infrared saunas, etc. These unstable electrons can contribute to brain disorders (Alzheimers, Parkinsons included). PIP can contribute to the biofilm problem, and kill desirable commensals. PIP polarizes and inhibits lymph drainage, and can harden lymph nodes.
The biofilm and PIP problems go deep into inflammatory tissue, remaining undetectable by EAV, kinesiological, and bioenergetic scans or methodologies.
Marine life is rich in zero-point energy (frequencies become one) when high negative ions predominate. This can remove PIP-generated inflammation. Negative ions increase oxygen flow in the brain.
The best lipids to address these problems are polar lipids. Polar means it is attracted to water. The carboxyl end of the lipid molecule is normally polar. Most lipids have parts of their makeup that is polar and parts that are not. This is neither good nor bad. A monosaturated oil such as found in olive oil (oleic) and butter is considered healthy. The problem comes with needing more polar oils in correcting many health conditions. Lipid degradation (oxidation) in the bottling or encapsulation can cause loss of native polar lipids.
Along with polar lipids the body needs cultured protein (yogurt, kefir, cream cheese, etc.) for regeneration. Besides the commoner sources of cultured protein, a commercial source has been made from microalgae that is preserved with CO2 Haematococcus pluvialis.
Mycotoxicosis is yet another problem. Mycotoxins means poison from fungi (commonly called molds). Most are aerobic. Aflatoxins, found in peanuts, soybeans, grains, and apples, can cause mycotoxicosis (misinterpreted as allergies). Ergot alkaloids, fumonsins (moldy corn), trichothecenses (seen in Russia), and vomitoxin (moldy wheat and corn), are others. Food irradiation effects can increase the incidence of myotoxicosis. Mycotoxins paralyze commensal cells and impair the immune system.
Correct cell polarity and resonance is needed for proper cell voltage. Disrupted cell polarity causes prolonged inflammation and leucocytosis (increased white blood cell numbers).
Inflammatory conditions (almost all illnesses) involves backed up lymph with cytokine inflammation (cytokines are small cell-signaling proteins that result in inflammation). (Cytokine storm is the reason for feeling bad at the onset of a flu, and when dramatically increased as postulated in H5N1, it has been related to higher mortality.)
All this points to detrimental effects, especially long-term, of the use of synthetic vitamins, overuse of most drugs (including hormone replacement therapy), overuse of non-polar lipids, and imbalanced body mechanics.
There are neuromuscular palpation techniques that can ascertain some of the above-discussed abnormalities. For example, properly trained medical practitioners may test the splenius capitis, the latissimus dorsi, and sacrospinalis (erecta spinae).
Furthermore, all this ties in with Neuro-Metabolic Analysis that relates to metabolic typing with specific urine analysis. Using all these ideas, we can come up with a protocol that gets closer to the cause of health problems for the least long-term cost.